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A serious road accident involving a motorbike cuts short the bus journey to work for Jasmine Hopkins & Julie Fitzjohn. Meanwhile, back at Holby City, new cardio-thoracic surgeon Alex Adams and new junior nurse Sandy Harper are immersed in a struggle to cope with the chaos caused by an infection scare.

Victoria Merrick is thrown into the deep end in pediatrics. Jasmine Hopkins's traumatic past helps her care for a patient who's convinced she has ovarian cancer.

When a well-known hospital fundraiser, John Wooldridge, demands a risky operation, Mike Barratt has to decide whether to refuse, or bow to management pressure.

The pressure is mounting for Julie as her trial period as ward sister comes to an end. Difficult patients, incompetent staff and domestic problems all contribute to making this a day from hell. Meanwhile, Steve is proved right when an apparently straightforward case turns out to be something far more sinister.

Sandy makes a play for Adams at the hospital party. Kirstie takes hospital rules into her own hands when she gives an elderly patient an unlicensed drug.

Keri befriends a teenage runaway with a guilty secret. Kirstie performs a dangerous emergency rescue. Victoria teaches a difficult patient a lesson.

Jasmine's involvement with a patient causes a stir on the ward. Mike has to make a difficult decision. Romance is in the air as Sandy plays Cupid.

Meyer faces his greatest challenge when his surgical career is threatened by illness. Is he capable of operating on eminent surgeon and former teacher Ian Richards? Julie is forced to reassess her priorities when her daughter, Rosie, is taken seriously ill.

With her daughter's life in jeopardy, Julie believes that only Meyer can save her. But is Meyer up to the challenge? Stan and Danny set about putting on a show for the children in Otter ward.

Tensions run high on Otter Ward when a major road traffic accident brings tragedy to one family as they face up to the death of their son, and joy to another as they are told that their daughter can have a long-awaited heart transplant. Meanwhile, Dr Taylor gets tough with Keri.

Janice Taylor finds herself at the centre of a legal battle when a teenage girl refuses life-saving treatment. Kath attempts to reconcile an estranged couple.

Tash faces a professional crisis when a patient fails to come round after an operation. Steve and Jasmine confront danger as they hunt for a missing boy. Dr Taylor clashes with an over-protective mother. Keri has to deal with an unexpected visitor to the ward.

Mike's day gets off to a bad start when a politician dies during a routine operation - and when a newspaper reporter gets hold of the story, things go from bad to worse. Alex solves a riddle with welcome consequences for a new mother.

Its a tricky night for the otter ward staff when a young nurse takes it apon herself to take part in a round of the ward with possible tragic concequences. Victoria manages the situation and gets her first ""well done "" from her boss Janice Talyor.

Janice Taylor becomes emotionally involved with a young patient when he demands more than medical help after his mother dies. Victoria Merrick jumps to conclusions when she treats a young teenage girl with amnesia and bruising.

An ex-alcoholic is admitted with a bleeding oesophagus: his wife suspects that he's been drinking again, but is it fair to jump to conclusions? Meanwhile, the staff of Darwin Ward celebrate too hard in advance of Liam Evans's wedding, which does not go according to plan.

Tash Bandara faces difficult personal and professional decisions when her estranged father pays her a visit and is diagnosed with a serious illness. Meanwhile, Liam Evans helps melt the ice between two dancing partners whose feelings for each other are more than just work-related.

Danny Shaughnessy faces a career crisis when he reveals more than he intends to a 15-year-old patient, and Keri McGrath finds herself embroiled in a mother/daughter conflict. Meanwhile, young love on the ward encourages Victoria to reconsider a romantic proposition.

Alex Adams's professionalism is under the spotlight when he becomes irate with a young heart-transplant patient who forces him to confront his past. Dr Anil Bannerjee's competence is questioned when a patient claims to have been awake under general anesthetic during an operation.

When Julie Fitzjohn adopts the role of mediator in an effort to reconcile a dying man with his estranged son, she is soon forced to reflect on her own situation.

The arrival of a childless couple on Keller Ward forces Kath Shaughnessy to face up to changes in her relationship with her son, Danny.

An allegation of professional misconduct pushes Steve Waring to the brink, and his relationship with Jasmine Hopkins is tested when he calls on her for help.

Anton Meyer's absence leaves laid-back Professor Alan Fletcher in charge.