Seasons & episodes

Jesse grows up gender fluid in a household rife with addiction, trauma and dysfunction; after nearly losing his mother to drugs, Jesse spirals into an addiction of his own and now lives on the streets.

Ashley has managed to stay away from her family's vices and get into one of the top universitie but her path strayed when her stepfather introduced her to heroin and meth.

After a terrifying burn accident as a child, Jayden grows up hoping to become a firefighter and fight California's notorious forest fires; after a series of tragic events, 20-year-old Jayden now smokes dangerous amounts of fentanyl.

Elliot overcame a traumatic childhood and moved to Las Vegas to pursue his dream of becoming a chef, but the rampant drug culture in restaurant kitchens along with the sudden death of his brother sent Elliot reeling.

When Ryan severely injured his ankle, doctors prescribed opioids; Ryan, couch-bound for a year, enjoyed the emotionally numbing effect of the drugs; now 26, he is addicted to fentanyl and has nearly lost his life to overdose multiple times.

When a family secret is accidentally revealed to Brea, the world she's known her entire life is shattered; as she begins to tailspin out of control with the help of alcohol and pharmaceuticals, all her mother can do is fight to pick up the pieces.

Raised in Northern California, Kenny excelled in football and had big dreams of playing in the NFL, but a misstep in high school triggered a series of events that left him homeless and addicted to dangerous amounts of fentanyl.

When Christine's brother died in a tragic accident, she turned to methamphetamine and her seemingly perfect family spiraled out of control; interventionists Ken Seeley and Sylvia Parsons team up on the biggest case of their careers.

Despite multiple overdoses and medical emergencies, Christine and her three adult children continue to use dangerous amounts of fentanyl together in their single studio apartment in Garden Grove, Calif.

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No episode summary available yet.

Amber Rose travels home to South Philadelphia to come to the aid of her childhood best friend Tina, who's addicted to fentanyl and crack. But first, she must find her.

Nick, and his girlfriend, Emily, are heavily addicted to carfentanil. Nick's family has stepped up to offer their son -- and Emily -- a final shot at getting clean.

Three addicted brothers have turned their childhood home into a hellish drug den where death is constantly at the door. As the brothers continue to struggle with the extreme abuse they suffered growing up, their mother sinks under the stress of continuous using, violent fighting and overdoses that have become the norm.

Jessica, a former high school beauty queen, is now just a shadow of her former self; as a teen mom, Jessica went to college and did her best to provide for her children, but a toxic ex introduced her to the drug trade.

Nineteen-year-old Melissa, once a star athlete who spent her free time volunteering, experiments with drugs and alcohol is eventually lured into the dark world of sex trafficking after experiencing a sexual assault as a young teen.

Tim and Jessica, both 43, first met in the 6th grade but three years ago they reconnected on Facebook and embarked on a chaotic.

When devoted animal rescuer, Shannon, develops a drug addiction, the one thing she can't seem to rescue is herself; childhood trauma, sexual abuse and toxic relationships become an explosive mix.

For Gabby and Patryk, it was love at first sight, 9 months later, Gabby gave birth to their daughter; they both happen to be heavily addicted to drugs, and the drug dealing lifestyle; their using has cost them custody of their daughter.

Disappointed by his own failed athletic career, Greg's father had found a new life in drugs and alcohol, and ultimately introduced his own son to crack cocaine; now 31, Greg is addicted to a deadly mix of fentanyl and meth and living on the streets.

Erika and Joey used meth together on their first date, beginning a drug-fueled romance; Joey's family refuses to be around Erika, leading to tension in the relationship; both families must come together to save them.

Josh's struggle with addiction threatens to destroy him; separated from his father and bullied for years, he's lost his way, leaving his family to fight for his survival amidst the chaos and violence fueled by crack cocaine.

Tommy and Melly, both 19, have had a troubled life for two people so young; both grew up in hardworking families, surrounded by a lot of love, but also a lot of pain; they are spiraling into fentanyl and meth addiction.

Cassandra and Steven met in a rehabilitation center five and a half years ago; after leaving treatment, they moved in together and shortly thereafter were engaged to be married; both quickly relapsed, spiraling deep into addiction.