Seasons & episodes
S4 · E9David Arquette 2010-01-18 · 30 min
David Arquette is back and telling us all about his new play The Female of the Species and the Golden Globes! Comedians Michelle Collins and Randy and Jason Sklar
S4 · E10Adrianne Palicki 2010-01-19 · 30 min
Clear eyes, full hearts, can't lose with Legion's Adrianne Palicki (aka FNL's Tyra). Comedian Chris Hardwick, actress-comedian Arden Myrin and comedian Eric Price.
S4 · E11Kaley Cuoco 2010-01-20 · 30 min
Who wouldn't be stoked that Kaley Cuoco from the megapopular Big Bang Theory is here? Comedian Heather McDonald, TV personality Ross Mathews and comedian Lavell Crawford.
S4 · E12James Van Der Beek 2010-01-21 · 30 min
James Van Der Beek is in the new movie Formosa Betrayed and popping up all over TV—even here! E!'s own Michael Yo, comedian Sarah Colonna and comedian Guy Branum.
S4 · E13Katharine McPhee 2010-01-25 · 30 min
No episode summary available yet.
S4 · E14Jill Scott 2010-01-26 · 30 min
No episode summary available yet.
S4 · E15Dax Shepard 2010-01-27 · 30 min
No episode summary available yet.
S4 · E16Staff Book Club 2010-01-28 · 30 min
No episode summary available yet.
S4 · E17Camila Alves 2010-02-01 · 30 min
No episode summary available yet.
S4 · E18Andy Whitfield 2010-02-02 · 30 min
No episode summary available yet.
S4 · E19Shorty Rossi 2010-02-03 · 30 min
No episode summary available yet.
S4 · E20Julie Benz 2010-02-04 · 30 min
No episode summary available yet.
S4 · E21Ozzy Osbourne 2010-02-08 · 30 min
No episode summary available yet.
S4 · E22Amanda Seyfried 2010-02-09 · 30 min
No episode summary available yet.
S4 · E23Dave Salmoni 2010-02-10 · 30 min
We're beyond pleased to welcome back our animal guy Dave Salmoni and his new animal friends. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Mo Mandel.
S4 · E24Channing Tatum 2010-02-12 · 30 min
No episode summary available yet.
S4 · E25Kate Flannery 2010-02-15 · 30 min
We get down to business with The Office's Kate Flannery. Comedian Loni Love, comedian Dan Levy and comedian Whitney Cummings.
S4 · E26Jackie Collins 2010-02-16 · 30 min
Things get really scandalous when author Jackie Collins stops by with her new book, Poor Little Bitch Girl. Comedian Chris Hardwick, comedian Jen Kirkman and comedian Jo Koy.
S4 · E27Lisa Edelstein 2010-02-17 · 30 min
Lisa Edelstein from House is back again...Wait, so who's running Princeton Plainsboro? Comedian Josh Wolf, comedian Heather McDonald and comedian Ryan Stout.
S4 · E28Eli Roth 2010-02-18 · 30 min
No episode summary available yet.
S4 · E29Keshia Knight Pulliam 2010-02-22 · 30 min
House of Payne's Keshia Knight Pulliam is one hard working lady; Dr. Huxtable would be so proud. Comedian Loni Love, TV personality Rove McManus and comedian Michelle Collins
S4 · E30Danica Patrick 2010-02-23 · 30 min
We're pretty thrilled that Danica Patrick makes a pit stop over at Chelsea Lately today. Comedian Josh Wolf, comedian Whitney Cummings and comedian Jo Koy.
S4 · E31Radha Mitchell 2010-02-24 · 30 min
Things might get wild with Radha Mitchell star of the new thrilling horror movie The Crazies. Comedian John Caparulo, comedian Bill Bellamy and actress-comedian Arden Myrin.
S4 · E32Parker Posey 2010-02-25 · 30 min
The Chelsea Lately cast do a Kardashian skit. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.