Seasons & episodes
S4 · E49Ludacris 2010-03-29 · 30 min
Ludacris is back with his new album Battle of the Sexes and this time he's bringing drinks. Comedian Ben Gleib, comedian Natasha Leggero and comedian Guy Branum.
S4 · E50Johnny Weir 2010-03-30 · 30 min
Johnny Weir is here, and unfortunately our show is not "on ice" this week. Comedian Jo Koy, comedian Lil JJ and comedian Sarah Colonna.
S4 · E51Erykah Badu 2010-03-31 · 30 min
No episode summary available yet.
S4 · E52Justin Bieber 2010-04-01 · 30 min
Chuy Bravo wrote a book, Little Nuggets of Wisdom, and he's here to share them. This, BTW, is all 100 percent for real, for real, girl. Comedian Heather McDonald, comedians Randy & Jason Sklar.
S4 · E53Jennifer Love Hewitt 2010-04-05 · 30 min
Author of The Day I Shot Cupid, Jennifer Love Hewitt is here. Comedian Brad Wollack, E!'s own Michael Yo and Comedian Mo Mandel,
S4 · E54Ed Asner 2010-04-06 · 30 min
Find out how spunky Chelsea can really be when TV Icon and star of Up Ed Asner stops by. Comedian Josh Wolf, comedian Loni Love and comedian Wil Anderson.
S4 · E55Blake MyCoskie 2010-04-07 · 30 min
Things get real philanthropic up in here with Tom's Shoes founder Blake Mycoskie. Comedian Greg Behrendt, comedian Jen Kirkman and comedian Matt Braunger.
S4 · E56Taraji P. Henson 2010-04-08 · 30 min
From the highly anticipated movie Date Night, the Academy Award-nominated Taraji P. Henson is here. Comedian Chris Franjola, comedian Chris Hardwick, TV personality Ross Mathews.
S4 · E57Tiny & Toya 2010-04-12 · 30 min
From BET's Tiny & Toya, BFFs Tiny & Toya are here. Comedian Whitney Cummings, actress Cloris Leachman and TV personality Ross Mathews.
S4 · E58Our 500th Episode 2010-04-13 · 30 min
Come celebrate a real milestone at Chelsea Lately—tonight's our 500th episode! Comedian Jo Koy, comedian Sarah Colonna and comedian Josh Wolf.
S4 · E59Dave Salmoni 2010-04-14 · 30 min
Resident animal expert Dave Salmoni is back with some hopefully furry friends. Comedian Dan Levy, comedian Arden Myrin and comedian Lavell Crawford.
S4 · E60Erin Andrews & Maksim Chmerkovskiy 2010-04-15 · 30 min
Dancing With the Stars' hottest couple Erin Andrews and Maksim Chmerkovskiy. Comedian John Caparulo, comedian Heather McDonald and comedian Donnell Rawlings.
S4 · E61Gretchen Wilson 2010-04-19 · 30 min
No episode summary available yet.
S4 · E62Amy & Matt Roloff 2010-04-20 · 30 min
No episode summary available yet.
S4 · E63Katie Cassidy 2010-04-21 · 30 min
No episode summary available yet.
S4 · E64Ted Allen 2010-04-22 · 30 min
No episode summary available yet.
S4 · E65Michael Weatherly 2010-04-26 · 30 min
No episode summary available yet.
S4 · E66Jerry Weintraub 2010-04-27 · 30 min
No episode summary available yet.
S4 · E67Jeffrey Dean Morgan 2010-04-28 · 30 min
No episode summary available yet.
S4 · E68Brooke Shields 2010-04-29 · 30 min
No episode summary available yet.
S4 · E69Molly Ringwald 2010-05-03 · 30 min
No episode summary available yet.
S4 · E70Busy Philipps 2010-05-04 · 30 min
No episode summary available yet.
S4 · E71Monica 2010-05-05 · 30 min
No episode summary available yet.
S4 · E72Michael Lewis 2010-05-06 · 30 min
No episode summary available yet.